Purpose of this paper is to describe process of gettingred wine and influence of its consumation on health of people. From olden times till now, culture of wine became very important on Europe. Starting from ancient Greeks, which were known for good wines, till now wine is nourished and shaped with great care. Process of making red is considerably different from process of making other wines. Red wine is made from fermentation of mash of red grapes. Characteristics of red wine comes from its content polyphenols , anthocyanins and tannins. Original Croatian sorts described in this paper are Plavac mali, Babić, Plavina, Dobričić and Crljenak kaštelanski. Plavac mali is most common sort of red wine in region of Central and South Dalmatia. In this paper is also described how moderate consumation of red wine has positive effect on human organism. Red wine contains resveratrol that positively affects cardiovascular disease. At the end of this paper is described why red wine is considered functional drink in Mediterranean diet.